Parkinson Disease

Research conducted at G. Villafane and co-researchers has updated our knowledge about Parkinson disease

Published in Drug Law Weekly, January 22nd, 2008

"Whether nicotine has therapeutic effects on Parkinson's disease (PD) symptoms is controversial, but high doses and chronic treatment have never been tested. We report the results of a pilot, open-label trial to assess the safety and possible efficacy of chronic high doses of nicotine," scientists writing in the European Journal of Neurology report.

"Six patients with advanced idiopathic PD received increasing daily doses of transdermal nicotine up to 105 mg/day over 17 weeks. All patients but one accepted the target dose. Nausea and vomiting were frequent but moderate, and occurred in most of the patients (four of six) who received over 90 mg/day and 14 weeks of...

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Source: Drug Law Weekly (2008-01-22)

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