Molecular Imaging
Studies from C. Dalessandria and co-researchers yield new data on molecular imaging
Published in Drug Law Weekly, March 11th, 2008
According to a study from Rome, Italy, "Crohn's disease (CD) is a chronic inflammatory bowel disease characterized by a cellular-mediated immune response driven by cytokines secreted mainly by T helper 1 cells (Th1). in active phases of the disease, an increased production and release of tumor necrosis factor alpha (TNF alpha) by macrophages and monocytes; of the lamina propria has been described. The aim of this study was to detect the presence of TNFa within the gut mucosa in patients with active CD by using Tc-99m-labelled chimeric human/mouse monoclonal antibody anti-TNF alpha (Infliximab, Remicade (R))."
"Infliximab has been labeled with Tc-99m after reduction of...
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Source: Drug Law Weekly (2008-03-11)
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