Life Sciences

Scientists at University of Southern California, Center for Craniofacial Molecular Biology discuss research in life sciences

Published in Drug Law Weekly, May 6th, 2008

Data detailed in 'Role of NBCe1 and AE2 in secretory ameloblasts' have been presented. According to a study from the United States, "The H(+)/base transport processes that control the pH of the microenvironment adjacent to ameloblasts are not currently well-understood. Mice null for the AE2 anion exchanger have abnormal enamel."

"In addition, persons with mutations in the electrogenic sodium bicarbonate co-transporter NBCe1 and mice lacking NBCe1 have enamel abnormalities. These observations suggest that AE2 and NBCe1 play important roles in amelogenesis. In the present study, we aimed to understand the roles of AE2 and NBCe1 in ameloblasts. Analysis of the data showed...

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Source: Drug Law Weekly (2008-05-06)

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