Life Sciences

Data on life sciences detailed by researchers at Federal University

Published in Drug Law Weekly, July 15th, 2008

"The ability of UV radiation to stimulate color change in vertebrates is well known; however, the signaling pathway involved is not fully explained. Since nitric oxide (NO) is among the candidates for this role, in this study the participation of NO signaling in the pigment migration induced by UV radiation in melanophores of the crab Chasmagnathus granulatus was investigated," investigators in Brazil report.

"When the NO donor, SIN-1, was incubated with pieces of epidermis, there was an induction of a dose-dependent pigment dispersion (in vitro assays). When male adults were exposed to different doses of UVA and UVB, N-G-nitro-L-arginine-methyl-ester, an NO synthase...

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Source: Drug Law Weekly (2008-07-15)

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