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Bladder Cancer Therapy

Recent findings from Zhejiang University, Department of Urology highlight research in bladder cancer therapy

Published in Drug Law Weekly, July 29th, 2008

Data detailed in 'Up-regulation of p21WAF1/Cip1 by saRNA induces G1-phase arrest and apoptosis in T24 human bladder cancer cells' have been presented. "Very recent studies have reported that chemically synthesized small duplex RNAs complementary to the promoters of target genes can activate gene expression in different cancer cell lines. Such dsRNA have been referred to as saRNA for small activating RNA," researchers in Hangzhou, People's Republic of China report.

"The present study was conducted to evaluate the potential of p21(WAF1/Cip1) (p21) induction by small activating RNA targeting the p21 promoter in the treatment of bladder cancer. Using T24 human bladder...

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