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Scientists at University of Tokushima report research in life sciences

Published in Drug Law Weekly, September 16th, 2008

Scientists discuss in 'Tomoeones A-H, cytotoxic phloroglucinol derivatives from Hypericum ascyron' new findings in life sciences. "Phloroglucinol derivatives tomoeones A-H (1-8) and three known compounds were isolated from leaves of Hypericum ascyron. Their structures were established based on spectroscopic analyses," scientists writing in the journal Phytochemistry report.

"They are all acylphloroglucinol derivatives possessing a spiro skeleton with geminal isoprenyl groups and a monoterpene moiety, and they are stereoisomers to each other at C-4 and C-13. They appear to be a class of phloroglucinol derivatives. Cytotoxicities of the isolated phloroglucinol...

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