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Study findings from Nagoya City University provide new insights into life sciences

Published in Drug Law Weekly, September 30th, 2008

Research findings, 'Cell-culture-dependent change of Ca2+ response of rat aortic myocytes to sphingosine-1-phosphate,' are discussed in a new report. "We characterized the effects of sphingosine-1-phosphate (S1P) on rat aortic myocytes with or without culture. Application of S1P induced a small Ca2+ response in 40% freshly dispersed aortic myocytes, whereas S1P caused a larger Ca2+ response in 90% myocytes cultured for 72 h," scientists in Nagoya, Japan report.

"Concentration-response relationships of S1P in cultured myocytes were significantly different from that in non-cultured myocytes. Analysis of the expression of S1P-receptor mRNA transcripts revealed that...

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