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Pharmacology

Research from Gifu Pharmaceutical University, Pharmacology Department in the area of pharmacology published

Published in Drug Law Weekly, October 7th, 2008

New research, 'Astaxanthin, a dietary carotenoid, protects retinal cells against oxidative stress in-vitro and in mice in-vivo,' is the subject of a report. "We have investigated whether astaxanthin exerted neuroprotective effects in retinal ganglion cells in-vitro and in-vivo. In-vitro, retinal damage was induced by 24-h hydrogen peroxide (H2 O2 ) exposure or serum deprivation, and cell viability was measured using a WST assay," scientists in Gifu, Japan report.

"In cultured retinal ganglion cells (RGC-5, a rat ganglion cell-line transformed using E1A virus), astaxanthin inhibited the neurotoxicity induced by H2 O2 or serum...

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