Life Sciences
New life sciences findings from University of Heidelberg, Division of Nephrology described
Published in Drug Law Weekly, November 18th, 2008
A report, 'Oxidative stress after uninephrectomy alters heart morphology in the apolipoprotein E -/- mouse,' is newly published data in Journal of Hypertension. "Even minor reduction in glomerular filtration rate accelerates atherogenesis and increases cardiovascular risk. The current study on the apolipoprotein E -/-mouse was designed to investigate whether nephron reduction by uninephrectomy causes cardiac remodeling and whether this is prevented by antioxidative treatment," scientists in Heidelberg, Germany report.
"We randomized apolipoprotein E -/-mice to undergo uninephrectomy or sham operation and subsequent treatment with either Tempol, Ebselen,...
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Source: Drug Law Weekly (2008-11-18)
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