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Teva Pharmaceutical Industries Ltd.

AZILECT Shown to Be a Selective MAO-B Inhibitor

Published in Drug Law Weekly, November 18th, 2008

Teva Pharmaceutical Industries Ltd. (NASDAQ: TEVA) announced results of a study in which Azilect(R) (rasagiline tablets) demonstrated selective MAO-B inhibition at the approved dose of 1mg. Non selective MAO inhibitors may have some contra indications with certain foods and drugs. These limitations are not associated with selective MAO inhibitors and therefore they can be broadly prescribed.

Based on these positive results, Teva will work with the U.S. Food and Drug Administration (FDA) to modify the AZILECT(R) label to reflect this data.

Selectivity was tested by evaluating the interaction between tyramine and rasagiline in healthy subjects. This...

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