Cardiopulmonary Bypass

Research from T.R. Rani and colleagues has provided new data on cardiopulmonary bypass

Published in Drug Law Weekly, December 2nd, 2008

According to recent research from Hyderabad, India, "THE ACTIVATED COAGULATION TIME (ACT) is commonly used to monitor heparin anticoagulation during cardiac surgery with cardiopulmonary bypass (CPB). Prolongation of the ACT can also result from coagulation factor deficiencies, producing a clinical dilemma."

"Congenital hypofibrinogenemia is a rare inherited coagulation disorder with only about 250 reported cases. I Patients with hypofibrinogenemia remain asymptomatic until fibrinogen levels are < 60 mg/dL. The routine preoperative screening tests of coagulation are insufficient to detect subtle disorders of fibrinogen. The authors found no previous reports of the...

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Source: Drug Law Weekly (2008-12-02)

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