Life Sciences

Researchers from Copenhagen University, Center for Clinical Intervention publish findings in life sciences

Published in Drug Law Weekly, February 17th, 2009

Investigators publish new data in the report 'Can trial sequential monitoring boundaries reduce spurious inferences from meta-analyses.' According to a study from Copenhagen, Denmark, "Results from apparently conclusive meta-analyses may be false. A limited number of events from a few small trials and the associated random error may be under-recognized sources of spurious findings."

"The information size (IS, i.e. number of participants) required for a reliable and conclusive meta-analysis should be no less rigorous than the sample size of a single, optimally powered randomized clinical trial. If a meta-analysis is conducted before a sufficient IS is reached, it should...

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Source: Drug Law Weekly (2009-02-17)

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