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Gallstones

New data from China University illuminate research in gallstones

Published in Drug Law Weekly, February 17th, 2009

According to recent research from Shanghai, People's Republic of China, "In order to investigate whether (-)-Epigallocatechin-3-gallate (EGCG) can reduce the susceptibility to cholesterol gallstone formation in vivo, cholesterol gallstones mouse model was established with lithogenic diet. Compared with the Model group, the administration of EGCG (40 mg kg(-1) d(-1) and 80 mg kg(-1) d(-1), i.g., respectively) significantly reduced the gallstone formation rates and the serum lipid levels, also maintained the body weight at a relatively low level."

"Results of the microarray profiling assay showed the anti-inflammation effect of EGCG underlying affecting the hepatic...

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