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Pneumococcal Disease Vaccines

Study data from Wakayama Medical University update understanding of pneumococcal disease vaccines

Published in Drug Law Weekly, February 24th, 2009

Data detailed in 'Protection against systemic fatal pneumococcal infection by maternal intranasal immunization with pneumococcal surface protein A (PspA)' have been presented. According to a study from Wakayama, Japan, "Streptococcus pneumoniae is a leading causative pathogen responsible for various types of bacterial infectious diseases in children. The aim of this study was to evaluate the protection conferred against fatal pneumococcal infections during infancy by maternal intranasal immunization with pneumococcal surface protein A (PspA)."

"Four-week-old female BALB/c mice were immunized with PspA mixed with, or without, cholera toxin B (CTB) intranasally...

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