Breast Cancer
Research on breast cancer discussed by E.K.A. Millar and co-researchers
Published in Drug Law Weekly, February 24th, 2009
According to recent research from Sydney, Australia, "BAG-1 (bcl-2-associated athanogene) enhances oestrogen receptor ( ER) function and may influence outcome and response to endocrine therapy in breast cancer. We determined relationships between BAG-1 expression, molecular phenotype, response to tamoxifen therapy and outcome in a cohort of breast cancer patients and its influence on tamoxifen sensitivity in MCF-7 breast cancer cells in vitro."
"Publically available gene expression data sets were analysed to identify relationships between BAG-1 mRNA expression and patient outcome. BAG-1 protein expression was assessed using immunohistochemistry in 292 patients with...
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Source: Drug Law Weekly (2009-02-24)
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