Arthritis

Research from University of Strathclyde in the area of arthritis described

Published in Drug Law Weekly, March 10th, 2009

"Achieving remission in rheumatoid arthritis (RA) remains elusive despite current biological therapeutics. Consequently, interest has increased in strategies to re-establish immune tolerance to provide long-term disease suppression," researchers in Scotland report.

"Although dendritic cells (DC) are prime candidates in initiating autoreactive T cell responses, and their presence within the synovial environment suggests a role in generation and maintenance of autoreactive, synovial T cell responses, their functional importance remains unclear. We investigated the contribution made by plasmacytoid DCs (pDCs) in the spontaneous breach of tolerance to arthritis-related self...

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Source: Drug Law Weekly (2009-03-10)

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