Thyroid Disease

Study data from Tottori University, Medical Department update understanding of thyroid disease

Published in Drug Law Weekly, March 24th, 2009

According to a study from Nishimachi, Japan, "Pendrin is an apical protein of thyroid follicular cells, responsible for the efflux of iodide into the follicular lumen via an iodide-chloride transport mechanism. It is unknown whether pendrin is recognized by autoantibodies."

"Our objective was to examine the prevalence of pendrin antibodies in autoimmune thyroid diseases and compare with that of thyroglobulin, thyroperoxidase, TSH receptor, and sodium iodide symporter antibodies. In a prevalent case-control study, we analyzed the sera of 140 autoimmune thyroid disease cases (100 with Graves' disease and 40 with Hashimoto's thyroiditis) and 80 controls (50 healthy...

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Source: Drug Law Weekly (2009-03-24)

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