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Bipolar Disorder Cell Biology

Investigators at Shanghai Jiao Tong University target bipolar disorder cell biology

Published in Drug Law Weekly, April 21st, 2009

A report, 'Association study on the mitochondrial gene NDUFV2 and bipolar disorder in the Chinese Han population,' is newly published data in Journal of Neural Transmission. "Bipolar disorder is known to be subject to maternal transmission. Mitochondrial DNA has been suggested as playing a role in the illness," scientists in Shanghai, People's Republic of China report.

"NDUFV2, located on 18p11.31-p11.2, encodes an important subunit of mitochondrial NADH (complex I). Previous studies have reported the association of NDUFV2 with bipolar disorder in the Japanese and Caucasian populations. Whether it is also a susceptible gene in the Chinese population is unknown....

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