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Interferon

New interferon research from E.L. Boxer et al outlined

Published in Drug Law Weekly, May 12th, 2009

"The innate immune response, in particular the production of type 1 interferons, is an essential part of the mammalian host response to viral infection. We have previously shown that rinderpest virus, a morbillivirus closely related to the human pathogen measles virus, blocks the actions of type 1 and type 2 interferons," scientists writing in the journal Virology report.

"We show here that this virus call also block the induction of type 1 interferon. The viral non-Structural C protein appears to be the active agent, since expressing this protein in cells makes them resistant to activation of the interferon-beta promoter while recombinant virus that does not...

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