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Leukemia

New leukemia study findings have been reported from University of Bern

Published in Drug Law Weekly, May 19th, 2009

According to recent research from Bern, Switzerland, "Eosinophil differentiation, activation, and survival are largely regulated by IL-5. IL-5-mediated transmembrane signal transduction involves both Lyn-mitogen-activated protein kinases and Janus kinase 2-signal transducer and activator of transcription pathways."

"We sought to determine whether additional signaling molecules/pathways are critically involved in IL-5-mediated eosinophil survival. Eosinophil survival and apoptosis were measured in the presence and absence of IL-5 and defined pharmacologic inhibitors in vitro. The specific role of the serine/threonine kinase proviral integration site for Moloney murine...

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