Life Sciences
Study results from University Federal do Rio of Janeiro update understanding of life sciences
Published in Drug Law Weekly, June 2nd, 2009
Research findings, 'mCD14 expression in human monocytes is downregulated by ouabain via transactivation of epithelial growth factor receptor and activation of p38 mitogen-activated protein kinase,' are discussed in a new report. According to a study from Rio de Janeiro, Brazil, "The steroid ouabain is found in plasma and in many mammalian tissues, and is now considered as a hormone. In the immune system, ouabain regulates a number of lymphocyte functions, but little is known about its effects on monocyte function."
"Monocytes are important for adequate immune responses. The aim of this work was to analyze the effect of ouabain on mCD14 expression, a surface molecule...
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Source: Drug Law Weekly (2009-06-02)
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