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Drug Law Weekly

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Adenoma



Investigators at Teikyo University release new data on adenoma



July 14th, 2009

According to a study from Ichihara, Japan, "Somatostatin analogues such as octreotide are used to treat active acromegalic patients by reducing serum growth hormone (GH) levels. However, the acute effect of octreotide oil GH secretion differs among patients."

"To elucidate factors influencing the acute effect of octreotide, we collected data front 56 patients with somatotroph adenoma from two institutions. We analyzed the correlation of the following factors with the acute effect of octreotide: immunohistochemical staining of somatostatin receptor subtype 2A (SSTR 2A), presence of gsp mutation, proliferative potentials analyzed by Ki-67 staining index (SI). We found...


Source: Drug Law Weekly (2009-07-14)

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