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Metabolism

Recent findings from Johann Wolfgang Goethe University highlight research in metabolism

Published in Drug Law Weekly, August 25th, 2009

"During the last decades polymer-based nanomedicine has turned out to be a promising tool in modern pharmaceutics. The following article describes the synthesis of well-defined random and block copolymers by RAFT polymerization with potential medical application," scientists in Mainz, Germany report.

"The polymers have been labeled with the positron-emitting nuclide fluorine-18. The polymeric structures are based on the biocompatible N-(2-hydroxypropyl)-methacrylamide (HPMA). To achieve these structures, functional reactive ester polymers with a molecular weight within the range of 25000-110000 g/mol were aminolyzed by 2-hydroxypropylamine and tyramine (3%) to form...

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