Rotavirus
Research from University of Naples yields new findings on rotavirus
Published in Drug Law Weekly, September 22nd, 2009
According to recent research from Naples, Italy, "The mechanisms of diarrhea due to rotavirus infection in humans are not fully understood; no specific therapy is available, but orally administered human serum immunoglobulins are effective in blocking stool output. We aimed to investigate the effect of rotavirus on ion transport and the role of NSP4 in human-derived enterocytes, and to test the efficacy of human serum immunoglobulin in a model of rotavirus infection."
"Soon after infection, rotavirus induces active chloride secretion in enterocytes. This effect is evident before viral replication leads to cell damage and correlates with NSP4 production. Inhibition of...
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Source: Drug Law Weekly (2009-09-22)
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