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Urogenital Abnormalities

Researchers at Boston University target urogenital abnormalities

Published in Drug Law Weekly, October 13th, 2009

"Diethylstilbestrol ( DES), a synthetic estrogen widely prescribed to pregnant women during the 1940s70s, has been shown to cause reproductive problems in the daughters. Studies of prenatally-exposed males have yielded conflicting results," scientists in the United States report.

"In data from a collaborative follow-up of three U. S. cohorts of DES-exposed sons, we examined the relation of prenatal DES exposure to occurrence of male urogenital abnormalities. Exposure status was determined through review of prenatal records. Mailed questionnaires (1994, 1997, 2001) asked about specified abnormalities of the urogenital tract. Risk ratios (RR) were estimated by Cox...

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