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Heart Attack

Research from S.X. Zhou and co-authors in the area of heart attack published

Published in Drug Law Weekly, October 20th, 2009

"This study was designed to evaluate the effects of the antioxidant probucol on myocardial oxidative stress and collagen remodeling by determining type I and III collagen together with relevant collagen mRNA expressions in both the infarcted and non-infarcted myocardium in post-myocardial infarction (MI) rats. Acute myocardial infarction was induced by ligation of the left anterior coronary artery in rats," investigators in Guangzhou, People's Republic of China report.

"Rats surviving 24 h after MI were randomly assigned to the group treated with vehicle or probucol. Sham-operated rats served as controls. Cardiac hemodynamics, parameters of oxidative stress in...

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