Bone Research

Study data from Aichi Gakuin University update understanding of bone research

Published in Drug Law Weekly, January 5th, 2010

According to recent research from Nagoya, Japan, "Bisphosphonates (BPs) are clinically used for the treatment of bone metabolic abnormalities because they are powerful inhibitors of bone resorption. Osteonecrosis of the jaw has been observed after tooth extraction in a considerable number of BP-treated cancer patients, but the reason for this is not known."

"We studied the effects of BP on extraction socket healing in rats that were pretreated with BP prior to tooth extraction. Male Wistar rats (approximately 5 weeks old) were divided into experimental (BP) and control groups. In both groups, maxillary right second molars were extracted under general anesthesia. BP...

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Source: Drug Law Weekly (2010-01-05)

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