Hepatitis B Virus
New hepatitis B virus study findings have been published by scientists at Drexel University, Medical Department
Published in Drug Law Weekly, January 5th, 2010
According to recent research published in the journal Nucleic Acids Research, "In both research and therapeutic applications of RNA interference, it is often advantageous to silence several targets simultaneously. Toward this end, several groups have developed vectors that utilize the model of endogenously encoded micro (mi) RNAs, where a single RNA polymerase II promoter can drive the expression of multiple interfering RNAs."
"Stronger pol III promoters have been used to drive individual short hairpin (sh) RNAs, but to date, it has been necessary to repeat the promoter in each silencing cassette to achieve multiplexed expression from a single vector. Here, we...
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Source: Drug Law Weekly (2010-01-05)
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