Non-Small Cell Lung Cancer

Researchers from University of Maryland report recent findings in non-small cell lung cancer

Published in Drug Law Weekly, January 12th, 2010

"Both small cell and non-small cell lung cancer over-express somatostatin receptors (SSTR). P2045 peptide is an 11-amino acid somatostatin analog that binds with high affinity to SSTR and can be labeled with Tc-99m to gauge receptor prevalence or with Re-188 for 2.1 MeV beta radiotherapy," scientists in the United States report.

"To evaluate the safety of this approach, a phase I dose-escalation study of Re-188 P2045 in SSTR-positive lung cancer was performed. Patients were required to have stage IIIb or IV or recurrent non-small cell lung cancer or extensive stage or recurrent small cell lung cancer, performance status 0 to 1, and normal organ function. There were no...

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Source: Drug Law Weekly (2010-01-12)

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