Published in Drug Law Weekly, January 26th, 2010
"We sought to measure in vivo both the binding site density (B-max) and the radioligand affinity (1/K-D) of C-11-®-rolipram in the rat brain. We also studied 2 critical factors in small-animal PET scans: the influence of anesthesia and the difference in binding under in vivo and in vitro conditions. In vivo, B-max and K-D were...
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