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Myeloid Leukemia

Data on myeloid leukemia described by researchers at University of Texas

Published in Drug Law Weekly, January 26th, 2010

According to recent research from the United States, "Outcome of patients with acute myeloid leukemia (AML) and high-risk myelodysplastic syndrome (MDS) with chromosome 5 and 7 abnormalities (excluding del 5[q]) has been poor, with <10% of patients alive at 2 years. The authors investigated whether treatment with hypomethylating agents (5-azacytidine/decitabine) leads to an improved outcome."

"Between January 2004 and December 2007, 81 patients (37 [46%] with AML [>= 20% blasts]; 44 [54%] with high-risk MDS) with chromosome 5 and 7 abnormalities were treated with hypomethylating agents as their initial therapy. These included 68 patients with complex (>= 3)...

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