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Multiple Sclerosis

ALLOZYNE Announces Completion of Phase IA Trial by AZ01, a Long Lasting Interferon b for Treatment of Relapsing Remitting Multiple Sclerosis

Published in Drug Law Weekly, January 25th, 2011

2011 JAN 25 -- ALLOZYNE, Inc. announced, the completion of its first Phase IA clinical trial in healthy individuals for AZ01, a PEGylated form of human interferon beta-1b which is being developed for the treatment of relapsing remitting multiple sclerosis. The objectives of the Phase IA trial were to assess safety and tolerability profile in addition to defining its pharmacological properties. The results demonstrate that single administrations of AZ01 were well tolerated at all dosage levels tested. In addition, drug serum levels and interferon activity biomarkers were maintained well after administration in the highest dose groups indicating that once a month dosing may be a...

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