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Immunosuppression
Hormone Has Potential Use in Autoimmunity and Transplantation
March 31st, 2000
Researchers reported that a hormone called 1,25-dihydroxyvitamin D3 (1,25-OH2D3) has a significant immunosuppressive effect. When used with corticosteroids, this hormone also has a synergistic immunomodulatory and steroid-sparing effect. These findings, announced at the 56th Annual Meeting of the American Academy of Allergy, Asthma and Immunology (AAAAI), held in San Diego, California, show potential for use of 1,25-OH2D3 in combination with corticosteroids in autoimmunity or transplantation. Orathai Jirapongsananuruk, MD, and colleagues from National Jewish Medical and Research Center found that 1,25-OH2D3 significantly decreased lymphocyte...
Source: Drug Week (2000-03-31)
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