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Platelet Inhibitor Therapy



Tailored Use May Prevent Second Heart Attacks



March 31st, 2000

Researchers at Duke University Medical Center think they know why glycoprotein IIb/IIIa platelet inhibitor drugs, collectively known as "super aspirins," produce only modest benefit for patients with acute coronary syndromes: they are often being used on patients who gain very little benefit.

In the process of tabulating results on a trial of lamifiban, one of three intravenous super aspirins that have been tested, the researchers discovered that a simple blood test identified patients who benefited markedly when the drug was used. In those patients, improvement in the risk of death and a second heart attack was about 50%, compared to patients who received a...


Source: Drug Week (2000-03-31)

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