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Drug Resistance
Study Clarifies Definition of Anthracycline Resistance
March 31st, 2000
A recent study identified various situations in which resistance to anthracycline-containing combination chemotherapy (ACCC) occurred in breast cancer patients, and found that after second-line treatment, some patients were also resistant to other cytotoxic drugs while others responded favorably. In an attempt to establish response rates (RR) and duration to second- and third-line chemotherapy treatments in anthracycline-resistant patients, X. Pivot and colleagues used 1,335 metastatic breast cancer patients who participated in first line trials of ACCC at the University of Texas M.D. Anderson Cancer Center between July 1973 and April 1980. Four definitions of...
Source: Drug Week (2000-03-31)
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