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New Chemistry Being Developed For Delivery Of Neuroprotective Drugs

Published in Drug Week, September 14th, 2001

One approach to treating neurodegenerative disease such as Parkinson disease is to interfere with the chemistry involved. Thus, scientists study the brain's chemical pathways and try to identify potential roadblocks.

At the 222nd national meeting of the American Chemical Society, held August 26-30, 2001, in Chicago, Illinois, Virginia Tech researchers presented their advancements in the development of such roadblocks.

Monoamine oxidases (MAO) A and B and the neuronal form of nitric oxide synthase (nNOS) are two enzyme systems thought to be involved in neurodegenerative pathways in Parkinson disease. A synthetic compound which inhibits both enzymes,...

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