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Heart Failure

Hormonal Study Shows Valsartan Significantly Reduces Severity Marker

Published in Drug Week, December 14th, 2001

Results of the largest neurohormonal study ever conducted in patients with heart failure demonstrate that the angiotensin II receptor blocker (ARB) valsartan significantly reduces plasma brain natriuretic peptide (BNP), a key biochemical marker of heart failure progression.

The findings were presented in November 2001 at the American Heart Association (AHA) Scientific Sessions by Roberto Latini MD, head of the laboratory of cardiovascular pharmacology, Istituto di Ricerche Farmacologiche, Mario Negri, Milano, Italy. The Valsartan Heart Failure Trial (Val-HeFT) was sponsored by Novartis Pharma AG.

"BNP levels have been shown to correlate with cardiac...

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