Published in Drug Week, October 18th, 2002
Cisplatin is just one of several compounds typically incorporated into cancer chemotherapy regimens. One of the side effects of cisplatin is sensory neuropathy, a complication compounded by increased dosing. Neurotrophin-3 (NT-3) gene therapy may avert or reduce sensory complications in patients on cisplatin, according to a new study.
"Neurotrophin-3 (NT-3) promotes the survival of the large fiber sensory neurones that are impaired in cisplatin-induced neuropathy, and may therefore serve as a preventive...
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