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Drug Week

Susan Hasty, Publisher

Table of Contents . . . November 1st, 2002

Non-Subscriber - Summaries Only

Related Areas: Other Issues in Drug Week | Other Publications

Alzheimer Disease - Antipsychotic drug has few side effects

Technology - AI designed for telecommunications will speed drug development

Addiction Medicine - New drug may help recovering cocaine addicts

Diabetic Nephropathy - FDA approves Avapro (irbesartan) to slow kidney disease

HIV/AIDS Therapy - Novel agent effective against cytomegalovirus shedding

Pain Medicine - Positive phase I results reported with intranasal morphine

Rheumatoid Arthritis - Phase II clinical trial of AGIX-4207 initiated

Actinic Keratosis - Solarase marketing agreement announced by SkyePharma and Meditech

Aspergillosis - Itraconazole reduces amphotericin B efficacy against pulmonary aspergillosis

Atherosclerosis - Developer of HDL therapies begins second clinical study of RLT peptide (ETC-642)

Bone Fractures - E.C. approves MAA for recombinant protein treatment for tibia fractures

Cervical Cancer - Phase I/II study of RSR13 initiated

Chlamydia - Preclinical efficacy studies: Antex STD vaccine protects against infection

Choroidal Neovascularization - Results of small photodynamic therapy study reported

Compliance - InnaPhase signs technology agreement

Conscious Sedation - Sicor wins ANDA approval for propofol injection emulsion 10 mL

Diabetic Neuropathy - Patients with type 2 diabetes find walking easier after sulodexide treatment

Diphenhydramine - ACAAI: Sedating antihistamine may double risk of serious injury

Drug Delivery - New report examines drug delivery technologies

Dyslipidemia - New patent granted for Niaspan-based cholesterol products

Epilepsy - Pregabalin may not save epilepsy drug market from generic erosion

Glioma - U.S. issues two patents to protect chlorotoxin

Glucose Control - Enrollment for Symlin dose titration study completed

Helicobacter Pylori - FDA issues nonapprovable letter for Helicide

Hepatitis B Virus - FDA approves Hepsera for treatment of chronic hepatitis B

Juvenile Rheumatoid Arthritis - Clinical trials initiated to explore use of adalimumab

Legal Issues - Manufacturing process of Eprex in question

Lymphoblastic Leukemia - Web site provides patient eligibility information for clinical trials

Opioid Bowel Dysfunction - Enrollment for study of Alvimopan completed

Pain Management - IND filed for buccal fentanyl with Health Canada

Pediatric HIV/AIDS - Vitamin A supplements improve infant nutrition, but not infection risk

Postoperative Pain - Positive results reported from phase I/II study with Intranasal Ketamine

Prostate Cancer - Eligard 22.5 mg launched as palliative treatment for advanced prostate cancer

Regulatory Issues - Switching drugs from prescription to OTC raises concerns

Rheumatoid Arthritis - Initial accrual complete in HuMax-CD4 phase II study

Schizophrenia - Seroquel effective across full spectrum of schizophrenia symptoms

Schizophrenia - U.S. FDA issues approvable letter for aripiprazole

Smallpox - Phase I vaccine trial yields positive results

Smoking Cessation - OTC sales of quitting aids up, effectiveness down

Staphylococcus Aureus - Phase I study of Veronate initiated in premature infants

Stem Cell Transplantation - High-dose antibiotics can prevent etoposide-related infections

Stem Cell Transplantation - Mycophenolate mofetil effective against GvHD but carries high infection risk

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