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Drug Week

Susan Hasty, Publisher

Table of Contents . . . November 15th, 2002

Non-Subscriber - Summaries Only

Related Areas: Other Issues in Drug Week | Other Publications

Alzheimer Disease - OHSU takes part in unique treatment trial

Dementia - Alzheimer drug effective against vascular dementias

Adverse Drug Effects - Frequency of new type 2 diabetes evaluated in patients taking antipsychotics

Genital Herpes - Therapeutic vaccine's safety shown in clinical evaluation

Influenza - FluINsure vaccine results presented at ICAAC

Pulmonary Embolism - Abbott receives FDA approval to reintroduce Abbokinase

Sickle Cell Anemia - Fast track status announced for novel sickle cell anemia treatment

Urology - First dual-acting 5 alpha-reductase inhibitor approved for benign prostatic hyperplasia

Addiction Medicine - Worldwide license agreement for potential drug treatment announced

Anxiety Disorders - Expansion of Ampakine research collaboration announced

Appointments - Joseph Villafranca joins Neose executive team

Appointments - Oral medicines developer names expert in antiviral discovery and development as CEO

Appointments - Pharmaceutical company announces board and management changes

Appointments - Sleep, neurological products developer selects new worldwide drug development VP

Cancer Therapies - Agreement reached for development, commercialization of indolocarbazole

Cancer Therapy - NDA submitted for antiemetic

Chronic Myeloid Leukemia - NCI/CALGB trial of Genasense plus Gleevec begins

Chronic Obstructive Pulmonary Disease - Positive forecast made for tiotropium

Cystic Fibrosis - Collaboration funds phase II study of respiratory therapeutic

Diagnostics - Skin cholesterol consumer products may help determine heart disease risk

Drug Delivery - Web site details patented technology

Drug Design - RNA drug technology shows therapeutic promise against bioterror agents

Drug Development - Bristol-Myers Squibb receives FDA action letter on antihypertension drug

Drug Development - Collaboration focuses on therapeutics on G protein-coupled receptors

Drug Development - Launching pharmaceutical blockbusters: Investing early fuels maximum impact

Drug Development - Molecular regeneration medicine developer signs multiyear collaborations with Abbott Labs

Drug Discovery - AstraZeneca renews global license of simulation software

Drug Discovery - GPCR-targeted library used to discover a small molecule agonist

Drug Discovery - NIST grant awarded for clinical genomics software development

Endocrinology - Exclusive license for thyroid stimulating hormone suppressor announced

Endocrinology - New FDA-cleared calcitonin test launched in U.S., Europe

Ethics - Critics call researchers' ties to drug companies troubling

Female Sexual Dysfunction - Phase II clinical trial initiated for testosterone gel

Gastroenterology - Company acquires marketing rights to rectal gel mesalamine preparation

Gastroenterology - Protein therapeutic significantly reduces tissue necrosis, mucosal damage

HIV/AIDS Therapy - Novel method for viral reservoir eradication shows promise

HIV/AIDS Therapy - Novel noncytotoxic vaginal microbicide may help prevent HIV and other infections

HIV/AIDS Therapy - Vitamin E can prevent infection-induced T-cell apoptosis

Hepatitis C Therapy - PEGylated Infergen to be developed for hepatitis C infection

Hypertension - Atorvastatin decreases incidence of heart disease, stroke

Laboratory Techniques - High-throughput cell analyzer 'Opera' launched

Legal Issues - Progress of pending patent protection for Levoxyl updated

Neurodegeneration - Aegera grants Wyeth license to adenovirus technology

Non-Small Cell Lung Cancer - Phase III clinical trial of Xyotax for second-line treatment initiated

Ophthalmology - ISTA Pharmaceuticals submits CMC section of Vitrase NDA

Ophthalmology - Results of phase I/II trial in retinal detachment announced

Pharmacy Benefit Plans - Employers shifting more decision-making, financial responsibility to employees

Prostate Cancer - License and codevelopment agreement signed for late-stage drug

Pulmonary Medicine - Canada's drug authority approves Remodulin for pulmonary arterial hypertension

Regulatory Issues - Court overturns rules on pediatric drug testing

Respiratory Disease - Collaboration combines technologies for novel therapeutics

Respiratory Disease - Peptides for humanized pulmonary surfactant technology patented

Restenosis - Safety data reported from drug-eluting stent clinical trial

Schizophrenia - Newer generation, long-acting injectable antipsychotic improves quality of life

Schizophrenia - Patients with intolerance to one drug benefit by switch to quetiapine fumarate

Stem Cell Transplantation - Anti-CD40L antibody effects enhanced by immunosuppressive agents

Stroke - sNDA filed for Niaspan for reducing risk

Therapies - Growth in the U.S. diabetes markets lures pharmaceutical companies

Thrombosis - Phase I/II study of antiphospholipid syndrome immunotherapeutic discussed

Transgenic Medicine - Dow obtains patents for production of glycoproteins in plant systems

Transplant Medicine - Recruitment complete for phase IIa clinical trial in kidney transplantation

Ulcerative Colitis - Phase III trial for increased dosage mesalamine underway

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