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Drug Week

Susan Hasty, Publisher

Table of Contents . . . December 6th, 2002

Non-Subscriber - Summaries Only

Related Areas: Other Issues in Drug Week | Other Publications

Chemotherapy-induced Febrile Neutropenia - New data confirm the impact of once-per-cycle pegfilgrastim for neutropenia

HIV/AIDS Therapy - Gabexate mesilate, octreotide effective for pancreatic conditions

Chronic Kidney Disease - BMP-7 may prevent bone and vascular complications

Congenital Heart Disease - Phase III study shows Synagis reduces RSV hospitalization

Erectile Dysfunction - Spontaneous sex still possible despite Viagra's 1-hour delayed action

Rheumatoid Arthritis - New data demonstrate safety and efficacy of leflunomide

Ulcerative Colitis - Infliximab may induce clinical remission, reduce need for steroid use

Alpha Interferon - Schering-Plough settles royalty payment arbitrations

Alzheimer Disease - Thuris enters feasibility collaboration to test RapidAging

Asthma - Disease costs are driven by medications, work loss

Cancer Therapy - Company wins patent to protect lead compound, NC381

Cancer Therapy - Study: Tumor regression occurs after injection of DNA complex

Cardiovascular Diseases - Company gets IND for phase II trials with NCX 4016

Contraception - Ortho Tri-Cyclen Lo now available by prescription

Drug Complications - NCL launches campaign to educate about dangers of OTC pain medications

Drug Trends - Analysis: Company hopes to find growth in depression market with duloxetine

Duodenal Ulcers - Genpharm wins FDA tentative approval for omeprazole

Financing - Pharmion completes $40 million private placement

HIV/AIDS Therapy - Alternative therapy use may signal psychological, emotional problems

Heart Failure - Valsartan improves survival, reduces hospitalizations in HF patients not taking ACE inhibitors

Hepatitis C - Interim results of phase I Albuferon-alpha clinical trial promising

Hepatitis C - Pharmaceutical group identifies new class of CpG oligonucleotides

Hepatocellular Carcinoma - New evidence disfavors tamoxifen for primary liver cancer

Hormone Replacement Therapy - Halting HRT: Treatment alternatives and market impact

Infectious Disease - International distribution agreements inked for Nabi-HB, hepatitis B antibody product

Infectious Disease Therapy - Amikacin enhances rifampin activity against Mycobacterium ulcerans

Kidney Disease - Study: Fosrenol reduces hypercalcemia risk in end stage renal disease

Legal Issues - Court upholds Merck's patent for osteoporosis drug

Medication Safety - Drug-induced ocular side effects are wide ranging

Metastatic Breast Cancer - Paclitaxel-based chemotherapy increases survival by 31%

Metastatic Breast Cancer - Phase II trial of Navelbine plus Herceptin for HER2 looks promising

Regulatory Issues - Study calls for more testing of drugs in children

Schistosomiasis - Study points to dexamethasone as possible treatment adjuvant

Traumatic Brain Injury - Investigational new drug application filed for phase III study of dexanabinol

Tuberculosis Therapy - High relapse rate seen after "successful" drug-resistant TB treatment

Tuberculosis Therapy - SRL172 ineffective as treatment adjunct for HIV coinfected patients

Ventricular Fibrillation - Company adds new cardiology medication to its product line

Ventricular Fibrillation - FDA denies pediatric exclusivity for Cordarone I.V.

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