Susan Hasty, Publisher
Table of Contents . . . January 10th, 2003
Non-Subscriber - Summaries OnlyRelated Areas: Other Issues in Drug Week | Other Publications
HIV/AIDS Therapy - Cosalane additives improve intestinal absorption
Parkinson Disease - Rasagiline appears to be an effective therapy for early disease
Fabry Disease - Preliminary results reported from new clinical study of Replagal
Hairy Cell Leukemia - Data presented on Nipent shows its capability as a franchise compound
Hodgkin Lymphoma - Phase I trial data on novel bispecific molecule H22xKi-4 reported
Infectious Disease Therapy - Continuous linezolid infusion effective against resistant S. aureus
Malignant Glioma - Phase I/II data presented for IL13-PE38
Paralysis - Atorvastatin promotes a Th2 bias, reverses paralysis in CNS autoimmune disease
Acne - Phase IIa clinical trials initiated for PCL-016 in mild-to-moderate acne
Alzheimer Disease - Alzheimer and inflammation clinical trials results reported
Anthrax - Antibiotics combined with antigen-based vaccine protects guinea pigs against anthrax
Antithrombin Deficiency - Clinical safety and efficacy trial of rhATIII begins
Anxiety Disorder - Lexapro better than placebo in trial
Arthritis - Enbrel offered to additional 40,000 arthritis patients
Arthritis - Results announced from phase III study of Enbrel dosed once weekly
Atrial Arrhythmias - Pharmaceutical company reports oral absorption of RSD1235 in humans
Attention Deficit Hyperactivity Disorder - Atomoxetine to account for about 25% of ADHD drug sales
Barrett Esophagus - Approvable letter received for Photofrin; final approval expected in 2003
Brain Metastases - Update provided on regulatory status of RSR13
Breast Cancer - Herceptin pretreatment enhances Taxol's effect in ErbB2-overexpressing cells
Cancer Therapy - Additional phase I data presented on liposomal antisense agent
Cancer Therapy - Pilot program explores viability of cell-penetrating peptide-based drugs
Cataplexy - Update provided on prescription levels for Xyrem oral solution
Chronic Lymphocytic Leukemia - Genasense shows single-agent activity in patients with advanced CLL
Clinical Trial Guidelines - NCQA issues draft standards for Human Research Protection Accreditation Program
Depression - FDA approves Lexapro oral solution
Duchenne Muscular Dystrophy - Scientists reveal potential new approach to treating muscle degeneration
Erectile Dysfunction - New study of Viagra's onset finds most men respond within 20 minutes
Erectile Dysfunction - Study: Vardenafil HCl improves ability to maintain erection to completion
Exocrine Pancreatic Deficiency - Axcan to acquire worldwide rights to Panzytrat enzyme product
Gaucher Disease - Worldwide license agreement extends Zavesca partnership
Generic Drugs - Caraco Pharmaceutical signs new R&D agreement for 25 new drugs
Glioma - Cotara receives orphan drug designation in Europe
HIV/AIDS Therapy - Glutathione-loaded erythrocytes enhance antiretroviral treatment
HIV/AIDS Therapy - Leptin levels linked to antiretroviral-induced immune recovery
HIV/AIDS Therapy - Protease inhibitor prodrugs show improved pharmacokinetics
Health Information - No more medical roulette: Publisher says internet will change in 2003
Hepatitis B Immune Globulin Therapy - Liver transplant indication BLA submitted for Nabi-HB Intravenous
Hepatitis C Therapy - Civacir receives orphan drug designation
Hormone Therapy - Hormone therapy technology licensed From Wake Forest
Hypertension - Forest updates status of lercanidipine regulatory submission
Immunosuppression - Butyrate has multiple effects on human monocyte-derived DCs, macrophages
Infectious Disease Therapy - Azithromycin effective against Shiga toxin-producing E. coli
Infectious Disease Therapy - Yeast adhesin analogs can prevent intestinal C. albicans infection
Lymphocytic Leukemia - Phase II study data reported on rituximab + fludarabine immunotherapy
Macular Edema - Enrollment complete for in phase II trial for PME treatment
Malaria - New drug shows early promise
Medication Errors - Baxter launches enhanced bar coding and information system technology
Metastatic Breast Cancer - Enrollment for pivotal phase III trial of ABI-007 completed
Migraine - Clinical data: Zomig-ZMT delivers early and sustained headache response
Multiple Myeloma - Novel drug continues to show promise in early study
Multiple Sclerosis - Betaferon now available at room temperature in the E.U.
Multiple Sclerosis - MS patients on Rebif more likely to remain relapse free
Non-Hodgkin Lymphoma - Positive pivotal phase II/III clinical trial results achieved for Onco TCS
Non-Small Cell Lung Cancer - FDA approves Taxotere for first-line treatment of patients
Nosocomial Infections - Increasing antibiotic resistance a major hospital crisis
Ophthalmology - Bucillamine suppresses choroidal neovascularization in rat model
Organ Transplant Rejection - HuMax-TAC program announced
Osteoarthritis - Pennsaid wins approvable letter from Health Canada
Pain Medicine - Company announces SGX 355, drug development candidate for neuropathic pain
Pain Medicine - U.S. Patent issued on Contulakin-G to treat pain; CGX-1160 safety trial over
Percutaneous Coronary Intervention - Long-term treatment with clopidogrel and aspirin significantly cuts risk
Pharmacodynamics - Antiangiogenic agent, Neovastat, induces endothelial cell apoptosis
Pharmacokinetics - Diacetylmorphine degradation in cell culture studied
Postoperative Ileus - Enrollment complete for phase III POI study for alvimopan
Product Rights Acquisition - Barr to acquire currently marketed products, including Ziac
Psoriatic Arthritis - Infliximab is effective, safe in clinical trial
Regulatory Issues - FDA's new head pledges more action against misleading ads
Schering-Plough Corp. - Peg-Intron and Rebetol pass 150,000-patients-treated mark in U.S.
Sleep Apnea - Approval granted to expand marketing of Provigil in the United Kingdom
Stem Cell Transplantation - Granulocyte colony-stimulating factor can hasten pediatric recovery
Therapeutic Programs - Cancer/immunotherapy company updates progress in commercial strategies
Trends - More consumers are asking their doctors for drug samples by name
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