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Drug Week

Susan Hasty, Publisher

Table of Contents . . . January 17th, 2003

Non-Subscriber - Summaries Only

Related Areas: Other Issues in Drug Week | Other Publications

Diabetic Nephropathy - Sarpogrelate reduces urinary albumin excretion in type 2 diabetic patients

HIV/AIDS Pathogenesis - Morphine enhances macrophage infection through chemokine, coreceptor modulation

Adverse Drug Events - Suspected fatal side effects of drugs in children have risen over past decade

Drug Efficacy - Firefly molecule could quickly shed light on how well new drugs work

HIV/AIDS Therapy - Interleukin-2 improves CD4 cell recovery

Medication Errors - Organizations release new drug safety technology

Obesity Therapy - Orlistat promoted weight loss in overweight adults also following a diet

Rheumatoid Arthritis - Adalimumab is safe, well tolerated, and improves RA signs, symptoms

AIDS Outreach - Pfizer, Pfizer Foundation announce new and expanded HIV/AIDS initiatives

Acute Coronary Syndromes - Study: Subantimicrobial-dose doxycycline lowers C-reactive protein

Acute Myeloid Leukemia - Combination chemotherapy may produce remission

Adverse Drug Events - Mechanism of life-threatening drug-interaction of Lipobay/Baycol clarified

Allergic Asthma - Study finds omalizumab improves children's quality of life

Allergy - Claritin hits store shelves

Antibiotic Resistance - Survey: One-third of Americans use antibiotics inappropriately

Appointments - Simmon named VP of policy and public affairs

Attention Deficit Disorder - Data shows NEO-339 has similar effects to Ritalin

Autoimmune Disease - Clinical trial application filed for Humax-Inflam/MDX018

Bipolar Mania - Data suggest risperidone, used alone, can provide symptom relief

Breakthrough Pain - Positive results reported for intranasal morphine gluconate in cancer patients

Breast Cancer - Research: Zometa significantly reduces risk of bone complications

Breast Cancer - Z-FAST study to evaluate Femara and Zometa in postmenopausal women

Breast Cancer - Zoledronic protects bone density for premenopausal breast cancer patients

Cancer Immunotherapy - Vitamin B-6 is common pro-moiety for antibody-directed abzyme prodrug therapy

Cancer Therapy - Clinical data on Triapine presented at ASH meeting

Cancer Therapy - New study supports dose-dense chemotherapy regimen for cancer patients

Cancer Therapy - Systemic delivery of Advexin demonstrates safety in cancer patients

Chinese Herbal Medicine - Sho-saiko-to extract reduces hepatic inflammation, fibrosis in nonsevere cases

Clinical Trials - Datatrak clients achieve 100% of data entry, review online

Clinical Trials - New service launched to disseminate clinical trials information

Colon Cancer - DHA shown to inhibit human colon carcinoma in mice

Colorectal Cancer - Results of CeaVac clinical study released

Cystic Fibrosis - Phase I study completed on Corus 1020 antibiotic

Diet Drugs - Clinical calorie study tests top diet pills

Drug Costs - Survey: Many would buy prescription drugs outside of the U.S. to save money

Epilepsy - Keppra safe, well-tolerated, and effective for seizures in children under 2

Ethics - Health officials to push for legislation on child drug research

Fatigue - Company launches stimulant Lucidex (enteric coated caffeine)

Finance - Company touts promising experimental drugs, potential sales growth

Finance - MedManage Systems closes additional $3.5 million in funding

Finance - Pelikan successfully completes $14.0 million round of Series C financing

Generalized Anxiety Disorder - Lexapro reported to significantly reduce anxiety in patients with GAD

Generalized Anxiety Disorder - Research: Effexor XR relieves symptoms of depression and GAD

Generic Drugs - Watson announces generic product development alliance

Geriatric Depression - Study shows Paxil CR is safe and effective for the treatment of elderly depression

HIV/AIDS Therapy - Actinomycin D stimulates HIV replication

HIV/AIDS Therapy - CADA inhibits HIV, human herpesvirus 7 activity

Healthcare Access - Agreement on access to cheap medicines remains elusive

Healthcare Access - Biotech firm to slash AIDS drug price in Africa

Hormone Replacement Therapy - MedPanel releases HRT study results

Insulin Analog - Novo Nordisk submits new drug application in the U.S. for NN304

Leukemia - Combination of alemtuzumab, fludarabine phosphate effective, safe

Leukemia - Treatment shows promise in study of patients with relapsing disease

Lymphoma - Rituximab boosts response rate in relapsed and refractory disease

Market Trends - Report: Novel compounds to drive the neuropathic pain market

Metastatic Breast Cancer - Breast cancer vaccine trial completed

Migraine Headache - European launch of frovatriptan announced

Multiple Myeloma - Velcade patients experienced a reduction or stabilization of disease severity

Ovarian Cancer - Positive data presented from phase II trial of TLK286

Postoperative Nausea - Study highlights benefit of low-dose Kytril for PONV prevention

Prescription Medicine - Study: Consumers and physicians back development of personalized medicine

Product Rights - Sarafem rights acquired from Lilly for $295M

Prostate Cancer - Zyflamend herbal COX-2 inhibitor exhibits anticancer activity

Pulmonary Embolism - Study shows use of enoxaparin safe and effective, and cuts hospital stays

Regulatory Issues - FDA issues consumer alert on importing certain prescription drugs

Rheumatoid Arthritis - Phase I clinical trial of MLN1202 begins

Schizophrenia - Physicians may overestimate how reliably patients take schizophrenia meds

Stem Cell Transplantation - Defibrotide improves peripheral blood cell mobilization

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