Drug Week

Healthcare Insurance - Advocates warn New York not to restrict access to prescription drugs

Hepatitis C - Copegus launched at discounted price

Infectious Disease - Cephalosporin overuse can increase Clostridium difficile- associated diarrhea risk

Infectious Disease Therapy - Cefotaxime and ceftriaxone effective against Salmonella typhi in human macrophages

Infectious Disease Therapy - Phenylacetic acid inhibits penicillin G acylase production by Escherichia coli

Insulin Resistance - Bezafibrate improves glucose uptake and endothelial function in HIV patient

Ischemia - Positive results reported from phase II trial on MC-1

Legal Issues - Settlement reached with states on partial fill prescriptions

Legal Issues - Supreme Court hears arguments on state drug plans

Lung Cancer - Millennium initiates phase II clinical trial with Velcade

Malaria Therapy - Artesunate-atovaquone-proguanil regimen effective against refractory Falciparum

Management Changes - CEO Downey undergoing treatment; remains active in management

Management Changes - Dr. Robert L. Capizzi named to board of directors

Medication Errors - Blue Cross Blue Shield of Alabama and ePocrates establish alliance

Medication Noncompliance - Significant new purchase order announced

Mergers and Acquisitions - Steps completed to achieve $21M cost savings goal

Methadone Therapy - Drug has properties that identify it as an unusual, potentially, unstable opioid

Mucopolysaccharidosis - FDA panel backs Aldurazyme

Myelodysplastic Syndromes - Enrollment begins in phase II clinical trial with DN-101 for MDS

Non-Hodgkin Lymphoma - Scientists report on improved linker for yttrium isotope

Nonsteroidal Anti-Inflammatory Drugs - Ketorolac may have proinflammatory properties during systemic immune stimuli

Nutritional Supplements - Juvenon launches delivers anti-aging supplement

Pain Medicine - Durect enters agreement to formulate certain long-acting opioid drugs

Parkinson Disease - Study: Rasagiline effective in early stage Parkinson disease

Plague - New contract centers on developing a subunit plague vaccine

Pulmonary Complications - Ranitidine premedication significantly reduces acid GER during thoracotomy

Pulmonary Inflammation - Aerosolized adrenomedullin reduces inflammatory, profibrotic response

Regulatory Issues - Feds to begin clinical tests on drugs commonly prescribed for children

Schizophrenia - Moderate dose of amisulpride controls five dimensions of psychopathology

Schizophrenia - Study: Clozaril reduces risk of suicidal behavior 26%

Sexual Dysfunction - Avlimil improves sexual experience of women in clinical trial

Staphylococcus Aureus - Antibiotic kills bacteria highly resistant to mupirocin

Thrombocytopenia - SBIR grant received from NCI to develop therapeutic proteins

Transplant Medicine - Immunosuppressant drug prevents late rejection of transplanted kidneys

Treatment Compliance - Study: Concerns about side effects may delay migraine treatment

Tuberculosis Therapy - Active pulmonary rifampicin levels seen after standard dose

Tuberculosis Therapy - Decaprenolphosphoarabinose analogs active against Mycobacteria tuberculosis

Tuberculosis Therapy - Whole blood bactericidal activity useful as treatment efficacy marker

Type 2 Diabetes Therapy - Gliclazide increases insulin receptor tyrosine phosphorylation in muscle cells

Vaccine Development - Collaboration aims to develop a safe subunit vaccine

Venous Thromboembolism - Arixtra demonstrates benefit in MATISSE studies

Virology - KGI Professors win NIH grant to fight HIV drug resistance