Drug Week

Hypertension - Calcium channel blockers not any more effective than diuretics or beta-blockers

Hypertension - Flutamide is protective against end-organ damage in both male and female

Immune Deficiency - Campaign launched to for primary immunodeficiency; investigation settled

Immunosuppressive Regimen - FDA approves new indication for Rapamune

Juvenile Arthritis - Treatment with etanercept may increase risk for streptococcal osteomyelitis

Keloids, Hypertrophic Scars - VIT100 enters phase I study

Legal Issues - Director clarifies SEC action, company position

Leukemia - Imatinib mesylate abates growth factor secretion in chronic myelogenous leukemia

Lung Cancer - Gemcitabine and vinorelbine followed by docetaxel is effective

Lung Cancer - INGN 241 combined with radiation shows promise during preclinical testing

Lung Cancer - Irinotecan combined with cisplatin is a good treatment option

Mental Illness - Effectiveness of investigational drug to be evaluated for pediatric depression

Mergers and Acquisitions - FTC clears acquisition plans for pharma giants

Mergers and Acquisitions - Newly combined company to commercialize cancer, heart disease drugs

Mergers and Acquisitions - Report: Pfizer to conduct 'mass layoffs' after takeover

Mergers and Acquisitions - Women's healthcare products portfolio acquired from Pfizer

Mergers and Acquisitions - World's largest, research-based, pharmaceutical company created

Muscle Spasms - Muscle relaxer Flexeril reaches pharmacies

Myelodysplastic Syndromes - Fast track status granted for Revimid; agreement signed for Alkeran

Neuroscience - Gadolinium may cause cerebrospinal changes resembling hemorrhagic stroke

Obesity Therapy - Glucose-dependent insulinotropic polypeptide inhibitor may be anti-obesity drug

Ocular Neuropathies - INGENOtyping agreement signed

Ophthalmology - New cataract removal system debuted; conjunctivitis drug approved

Pain Medicine - Opioid antagonist product developed for abuse resistance

Parkinson Disease - Can cannabinoids counter drug side effects?

Patents - Additional patent granted for proprietary treatment of infectious disease

Personnel - Capello, Hirsch named VPs at dermatology company

Personnel - Fuster joins scientific advisory board at immune modulation company

Personnel - Industry consultant named to key drug development position

Personnel - Interim CEO, president named to lead strategic transformation

Personnel - Management change announced at biotech company following CFO's resignation

Personnel - New CEO named at U.K. biotech company

Personnel - Nigon, Peltier named as directors

Personnel - Schied retires as chief financial officer

Personnel - Sigal added to scientific advisory board

Personnel - Therapeutic RNA interference company says senior management team expanded

Personnel - Warner named chief scientific officer

Pharmacology - New isoquinolinone derivative has new mode of action on cardiovascular systems

Pulmonary Hypertension - S-Nitrosocaptopril shows promise for treating pulmonary hypertension

Refractory Cancer - Flavopiridol infusion therapy was unaffected by UGT1A1 polymorphisms

Research Alliance - Collaborative effort to identify cancer biomarkers

SEC Investigation - Pharmaceutical company produces documentation for SEC

Sciatica - Infliximab may reduce sciatica pain

Severe Pulmonary Hypertension - Long-term therapy with treprostinil improves survival

Sleep Disorders - Patent issued for proprietary compound for treatment of insomnia

Smallpox - Phase I smallpox vaccine clinical trial completed

Solid Tumors - Independent review of anticancer drugs reports initial clinical successes

Stock Market - Name change becomes effective; shares to be listed on AMEX

Therapeutics Screening - Extended Neurite Outgrowth BioApplication released

Type 2 Diabetes Therapy - Sulphonylureas affect K-ATP channels in different muscles selectively

Virus Defense - Research identifies molecular pathway related to infection-fighting mechanism