Drug Week

Molecular Biology - Chemist works to prevent undesirable side effects in synthetic drugs

Prostate Cancer - Long-term data show Zometa slows pain progression and reduces bone complications

Atorvastatin - Atorvastatin safely reduces dyslipidemia in patients with nephrotic syndrome

End-Stage Renal Disease - Sustained-release diltiazem reduces myocardial ischemic episodes

Hypercholesterolemia - New cholesterol drug paired with statin lowers cholesterol

Leprosy - Thalidomide finding new use as treatment for leprosy and other diseases

Obesity Therapy - Zonisamide promotes weight loss in obese patients

AIDS Prevention - Global fight against AIDS requires more than drug cocktails

Adverse Drug Effects - Electron microscopy aids diagnosis of NRTI-induced toxic effects in liver

Allergy Medicine - Promotion launched to help patients treat allergy symptoms

Amiodarone - Amiodarone is an old drug with new guidelines for pediatric resuscitation

Analgesic Efficacy - Preoperative test dose of i.v. fentanyl can predict analgesic efficacy

Angiogenesis - New scientific data disclosed on Neovastat

Anticancer Drugs - Quaternary ammonium-melphalan conjugate is a potential cartilage targeter

Antitumor Activity - Bortezomib has demonstrated antitumor activity in a variety of tumor types

Attention Deficit Hyperactivity - Studies demonstrate optimal dose ratio for Metadate CD

Autoimmune Myocarditis - NIH grant to be used for development of new heart disease treatment

Biodefense - Project aimed at Ricin toxin initiated with funding from CRTI

Blood Product Manufacturing - FDA approves new sterile filling facility for plasma proteins

Brain Metastases - Pivotal phase III trial results released for RSR13

Breast Cancer - No link seen between breast cancer risk and antidepressants

Cancer Therapy - Patent broadens technology platform to deliver radioactivity to cancer cells

Cancer Therapy - Potential anticancer applications of Virulizin expanded

Cancer Therapy - Preclinical data: Panzem inhibits hypoxia inducible factor

Cancer Therapy - Preclinical study shows INGN 241 drug effective for ovarian cancer

Cancer Therapy - Researchers review value of anticancer antibodies

Cancer Therapy - Researchers use DNA chips to determine how leukemia cells respond to treatments

Candida Albicans - Antifungals with common mechanism lead to similar effects at proteome level

Cardiopulmonary Resuscitation - After near drowning, spontaneous circulation can be restored after vasopressin

Cell Aging - Drugs temporarily make old visual brain cells act young in animal tests

Chemotherapy - A mathematical model may be useful for cisplatin dosing

Chemotherapy - Dosage regimen is optimized in cancer chemotherapy using a mathematical model

Chemotherapy - Thalidomide's suppression of embryonic fibroblasts depends on CYP1A1 activation

Chronic Primary Insomnia - Positive results reported from second phase III clinical trial with indiplon

Coinfection - HBV drug resistance in HIV-HBV infected patients calls for close monitoring

Collaborations - Cancer product licensing agreement announced

Communications - Biotech media development company announces launch

Coronary Artery Bypass - Tranexamic acid reduces bleeding after CABG in patients treated with aspirin

Corporate Expansion - Drug discovery company acquires new headquarters

Diabetes Risk Factor - Antipsychotic treatment linked to diabetes development

Diabetes Therapy - Captopril exerts direct effect on insulin action in BC3H-1 myocytes

Diabetes Therapy - New series of phenylacetic acid derivatives as hPPAR agonists synthesized

Drug Assistance Programs - Price of HIV drug Viramune is frozen

Drug Development - Piperaquine + dihydroartemisinin may work in chloroquine-resistant areas of Cameroon

Drug Development - Proteome mining company enters collaboration with MolecularNature

Drug Discovery - HIV-1 integrase inhibitory substances extracted from Coleus parvifolius

Drug Discovery - Novel mechanism for inhibition of HIV-1 reverse transcriptase reported

Drug Hypersensitivity - Effective tolerance induction protocol reported for HIV patients

Drug Interactions - Short-term exposure to low-dose ritonavir boosts trazodone's negative effects

Drug Interactions - Sildenafil does not alter nelfinavir pharmacokinetics

Drug Resistance - Genetic profile shows resistance to sulfadoxine & pyrimethamine highly likely

Drug Resistance - Study finds assays accurate for testing HIV-1 non-B subtypes

Endocarditis - Vancomycin treatment failure in a patient with endocarditis reported

Erectile Dysfunction - Tostrex Gel now called Fortigel

Estrogen Receptor - A new non-steroidal diphenylnaphthyl propylene ligand is antiestrogenic

Fabry Disease - FDA approves Fabrazyme, an enzyme replacement therapy

Finance - Biotech company reports net loss of $0.54 per share

Finance - Cardiovascular disease firm reports strong first quarter

Finance - Consensus earnings expectation of $0.28 per share achieved at biotech company

Finance - Drug delivery company reports net loss of $0.22 per share

Finance - Drug maker reports first quarter results, atherosclerosis update

Finance - Earnings per share reported at $0.26 for biologics contract service organization

Finance - Eligard maker reports 167% revenue increase

Finance - First quarter earnings per share increase 31% for biotech company