Dendritic Cell Vaccine
Cytomegalovirus-specific T cells stimulated using modified dendritic cells
Published in Drug Week, July 4th, 2003
"Cytomegalovirus (CMV) infection is a dangerous complication in immunosuppressed individuals such as allogeneic stem cell transplant patients. CMV disease can be prevented by the early post-transplant transfer of donor-derived, CMV-directed, T cells. Fast and cost efficient methods to generate CMV-specific T cells are, therefore, warranted," scientists in Sweden report.
"The current study utilized peptide-pulsed and adenovirus-transduced dendritic cells (DC) to generate CMV-restricted T cells," stated Bjorn Carlsson...
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Source: Drug Week (2003-07-04)
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