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Kidney Disease

BMP-7 reverses kidney injury

Published in Drug Week, July 18th, 2003

Curis, Inc., (CRIS) announced that the scientific journal Nature Medicine published online results of a study demonstrating the potential of using BMP-7 as treatment to both halt the progression and reverse the effects of chronic progressive kidney disease.

The publication, entitled "BMP-7 counteracts TGF-(beta)1-induced epithelial-to-mesenchymal transition and reverses chronic renal injury," was based on the research of Raghu Kalluri and his associates at the Beth Israel Deaconess Medical Center and the Harvard Medical School.

In the study, which is the first to demonstrate the potential of BMP-7 to promote reversal of the effects of chronic...

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