Anticoagulant Allergy

Danaparoid is successful in case of heparin induced skin reaction in pregnancy

Published in Drug Week, August 1st, 2003

Synthetic heparinoid, danaparoid, is successful in case of heparin therapy-induced skin reactions during pregnancy.

"Allergic cutaneous reactions to heparin are a diagnostic, but mainly therapeutic challenge because an alternative anticoagulant treatment is essential. We report the case of a 24-year-old woman who, during her first pregnancy, developed a delayed type hypersensitivity reaction induced by low molecular weight heparin (LMWH) given at a prophylactic dose," researchers in France report.

"Because this patient exhibited crossreactivity with all other available LMWHs, she was given a synthetic heparinoid (danaparoid, Orgaran), and this...

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Source: Drug Week (2003-08-01)

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