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DNA Vaccine

DNA vaccines for the rabies-related virus, Mokola, compared

Published in Drug Week, August 1st, 2003

DNA vaccines for the rabies-related virus, Mokola, were compared.

According to published research from the United States, "Mokola virus, a rabies-related virus, has been reported to date from the African continent only. Like rabies virus, it is highly pathogenic, causes acute encephalitis, and zoonotic events have been documented. Although believed to be rare, there has been an unexplained increase in the number of isolations of the virus in South Africa in recent years."

"We have cloned and sequenced the glycoprotein (G) and nucleoprotein (N) genes from a South African Mokola virus, and used these in the construction of different DNA vaccines for...

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